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Updated: Jul 15, 2025

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来自SARS-CoV-2的5'-UTR的干环4的高分辨率结构,通过溶液状态NMR解决

Jennifer Vögele1,2, Daniel Hymon2,3, Jason Martins2,3

  • 1Institute for Molecular Biosciences, Goethe-University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt/M., Germany.

Nucleic acids research
|October 4, 2023
PubMed
概括

研究人员确定了SARS-CoV-2关键RNA元素5_SL4的结构,揭示了对病毒功能和潜在药物向重要的结构性可塑性. 这种保存的RNA结构可能是小分子连接体的可行目标.

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