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心肌功能障碍对感染性休克儿童死亡率的影响:一项前性观察性研究
Ekin Soydan1, Mehmet Murat2, Ceren Karahan2,3
1Pediatric Intensive Care Unit, Dr. Behcet Uz Children's Hospital, University of Health Sciences, Izmir, Turkey. dr-ekinsoydan@hotmail.com.
European journal of pediatrics
|October 4, 2023
概括
心肌功能障碍在儿科败血症休克中很常见,影响50%的患者. 对三状环状平面缩外流 (TAPSE) z-score的心声测量是这些重症儿童死亡率的关键,易于评估的预测指标.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 关键护理医学 关键护理医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 儿科败血症休克涉及多器官和心血管功能障碍.
- 在儿科败血症休克中心肌功能障碍未得到充分研究.
- 心声学在儿科败血症休克管理中的作用缺乏具体指导方针.
研究的目的:
- 评估心声学确定心肌功能,疾病严重程度和儿科败血性休克的临床结果之间的关系.
- 为了确定可预测性休克儿童死亡率的回声心脏学参数.
主要方法:
- 对56名儿科败血症休克患者进行前性观察性研究.
- 心声图用于评估心缩和心缩功能.
- 对临床数据的分析,包括PRISM III,VIS,乳酸,CK-MB,热和各种心声指数 (EF,EF z-score,MAPSE z-score,TAPSE,TAPSE z-score,中心E/e' z-score,中心E/A,中心E/A z-score) 的分析.
主要成果:
- 50%的患者表现出心肌功能障碍 (心缩和/或心缩).
- 在PRISM III,VIS,乳酸盐,CK-MB,热素,EF z-score,MAPSE z-score,TAPSE,TAPSE z-score和中枢E/e'z-score中观察到死亡率的显著差异.
- EF z-score (OR=0.681) 和TAPSE z-score (OR=0.690) 与30天死亡率相关.
- 塔普斯z-score成为死亡率的最重要的独立风险因素.
结论:
- 左心室功能障碍是与儿科败血症休克死亡率相关的重要因素.
- 三环状平面缩外流 (TAPSE) z-score,反映了右心室功能障碍,是死亡率最强的独立预测指标.
- TAPSE是一种有价值的,易于测量的床边参数,用于监测患有败血症冲击的儿童.
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