血培养阴性传染性内心炎:我们是否足够努力?
Frazer Kirk1,2, Natasha Marcella Vaselli3,4,5
1Gold Coast University Hospital, Southport, QLD, Australia. frazer.kirk@my.jcu.edu.au.
Infection
|October 4, 2023
概括
血液培养阴性内心炎 (BCNE) 呈现出诊断挑战和显著的死亡率. 目前的诊断标准不敏感,需要改进在BCNE病例中识别生物体的方法.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医学诊断 医学诊断 医学诊断
背景情况:
- 传染性内心炎是一种普遍的心脏病,与高死亡率有关.
- 血培养阴性内心炎 (BCNE) 是一个具有相当严重发病率和死亡率的关键亚组.
研究的目的:
- 审查当前关于血液培养负性内心炎的文献和临床指南.
- 综合有关BCNE的诊断,原因和并发症的发现.
主要方法:
- 进行了最新的文献综述.
- 在Web of Science,MEDLINE,EMBAS和Scopus数据库中进行了搜索.
- 提供了收集的文学作品的叙事综合.
主要成果:
- 由于诊断途径不敏感,BCNE的原因和并发症存在显著的异质性.
- 尽管诊断工具的进步,对感染性内心炎的修改后的杜克标准仍然对检测BCNE不敏感.
结论:
- BCNE的自然史和诊断能力正在不断发展.
- 修改后的杜克标准需要更新以反映当前的理解和诊断资源.
- 临床医生应该关注疑似BCNE的负培养物,强调需要彻底识别生物体.
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