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在患有CHAGASIC MEGAESOPHAGUSUS的患者中共同疾病的流行
Arthur Marot de Paiva1, Gabriel Baeta Branquinho Reis1, Pedro Henrique de Ávila Perillo1
1Faculdade de Medicina da Universidade Federal de Goiás, Goiânia, GO, Brasil.
Arquivos de gastroenterologia
|October 4, 2023
概括
查加斯大食管患者出现高血压,脂质失调和心力衰竭的高率. 降低糖尿病和阿尔茨海默病的发病率表明与肠道神经系统缩有联系,需要进一步研究.
科学领域:
- 胃肠病学 胃肠病学
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 查加斯病可以导致大食道,一种影响食道的疾病.
- 查加斯大食管和其他并发症之间的关系尚未完全理解.
- 调查并发症可以揭示与大食道相关的保护性或风险因素.
研究的目的:
- 评估查加斯大食管患者中特定并发症的流行率.
- 为了比较患有和没有大食管的患者之间的并发症患病率.
- 为了确定查加斯大食道是否对分析的条件起到保护作用或风险因素.
主要方法:
- 观察性描述性研究.
- 从医疗记录 (2005-2020) 中收集的数据.
- 患者分为一般 (所有年龄) 和老年 (≥60岁) 组.
主要成果:
- 在546名一般患者中,高血压 (44.3%),脂质失调 (17.8%) 和心力衰竭 (15.2%) 是最常见的.
- 在248名老年患者中,高血压,脂质不良和心力衰竭也是最常见的.
- 在查加斯大食管患者中观察到糖尿病和阿尔茨海默病的较低患病率.
结论:
- 系统性动脉高血压,脂质不良和心力衰竭在这个人群中非常普遍.
- 糖尿病和阿尔茨海默病的发病率降低表明与肠道神经系统缩有联系.
- 需要进一步的研究,以探索查加斯巨食道中肠道神经系统缩的含义.
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