科罗特科夫声音生成的基本机制
Jerome Baranger1, Olivier Villemain1, Guillaume Goudot1,2
1Physics for Medicine Paris, Inserm, ESPCI PSL Paris, CNRS, Paris, France.
Science advances
|October 4, 2023
概括
在血压测量中使用的科罗特科夫声音不是来自臂动脉,而是周围组织的剪切振动. 这一发现澄清了它们的起源,并可能改善血压监测的准确性.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医学声学 医学声学
背景情况:
- 血压测量对于预测死亡风险至关重要.
- 使用Korotkoff声音的听觉方法是非侵入性血压评估的黄金标准.
- 科罗特科夫声音的确切起源仍在争论中,这限制了临床应用.
研究的目的:
- 为了阐明科罗特科夫声音的体内起源.
- 为了研究科罗特科夫声音生成的机制.
- 探索血压测量技术的潜在改进.
主要方法:
- 利用每秒数千的超快超声波成像来可视化科罗特科夫声音的产生.
- 结合实验观测与理论建模.
- 分析了剪切振动的传播及其与检测到的声音的相关性.
主要成果:
- 证明科罗特科夫声音具有悖论的不是来自手臂动脉的声音波.
- 通过非线性脉冲波传播在周围组织中传递的剪切振动来识别声音.
- 显示这些剪切振动是同步的,相关的,并且在强度上与科罗特科夫声音相比,当它们到达语听器时.
结论:
- 这项研究澄清了科罗特科夫声音作为剪切振动的矛盾起源.
- 了解这种机制可以提高血压测量的准确性.
- 提供了对动脉机械特性和非线性脉冲波传播的见解.
相关概念视频
01:12Korotkoff Sounds
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Korotkoff sounds are the specific sounds heard while measuring blood pressure using a sphygmomanometer, typically with a stethoscope or a Doppler device. They are named after Russian physician Nikolai Korotkov, who first described them in 1905. These sounds correspond to turbulent blood flow in the artery as the blood pressure cuff is gradually released after inflation.
During blood pressure assessment, inflating the cuff 30 millimeters of mercury above the patient's systolic blood pressure...
During blood pressure assessment, inflating the cuff 30 millimeters of mercury above the patient's systolic blood pressure...
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01:15Heart Sounds
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Heart sounds are generated by the turbulence in blood flow due to the closing of heart valves. These sounds are best perceived slightly away from the valves, where the blood flow disseminates the sound.
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
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01:28Special considerations while measuring blood pressure
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When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
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01:25Cardiovascular System Abnormal Findings II: Auscultation
162
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
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01:13The Cochlea
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The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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01:25Assessment of the Cardiovascular System IV: Auscultation
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Cardiac auscultation is a clinical skill used to assess heart function and detect abnormalities. It involves listening to heart sounds at specific anatomical locations through a stethoscope.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
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