与假牙相关的创伤性的唾液阿片水平
Mahmut Sertac Ozdogan1, Mustafa Gungormus2,3
1Department of Prosthodontics, Faculty of Dentistry, Ankara Yıldırım Beyazıt University, Ankara, Turkiye.
Oral diseases
|October 4, 2023
概括
唾液中的阿皮欧芬水平随着假牙相关的疼痛而增加. 调整不合适的假牙缓解了疼痛,并显著降低了阿片水平,表明其作为疼痛生物标志物的作用.
科学领域:
- 口服药是一种口服药.
- 生物化学 生物化学
- 疼痛研究 疼痛研究
背景情况:
- 一种唾液五的opiorphin表现出强大的止痛特性.
- 在 orofacial 疼痛条件下观察到升高的唾液opiorphin.
- 奥皮欧芬可能有助于缓解与假牙相关的的疼痛.
研究的目的:
- 为了评估因不合适的假牙造成的创伤性的个体的唾液opiorphin水平.
- 为了研究疼痛强度和唾液中阿皮欧芬度之间的相关性.
- 评估假牙调整对疼痛和阿片水平的影响.
主要方法:
- 招募了22名患有新的,不合适的假牙和疼痛的患者.
- 使用视觉模拟尺度 (VAS) 量化疼痛.
- 在牙套调整前和7天后收集唾液样本.
主要成果:
- 在调整后,唾液中的平均阿片水平从19.29 ± 5.44 ng/mL降至15.78 ± 3.95 ng/mL.
- 在假牙调整后,观察到阿皮欧芬水平的统计显著降低.
- 该研究发现,阿片水平增加与假牙相关的疼痛之间存在相关性.
结论:
- 在假牙相关的创伤性的存在下,唾液内opiorphin水平升高.
- 牙调整可以缓解疼痛,并导致唾液opiorphin的显著减少.
- 奥皮欧芬作为与不合适的假牙相关的疼痛的潜在生物标志物.
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