高耐力训练受试者之间的免疫代谢和血管健康反应
Henrique A R Fonseca1,2,3, Celia Regina Bittencourt1, Andrea Moreira Monteiro2,3
1Cardiology Division, Department of Medicine, Federal University of Sao Paulo, São Paulo, SP, Brazil.
International journal of sports medicine
|October 4, 2023
概括
高耐力训练对血管健康和免疫反应产生影响,特别是在男性中,对动脉内膜介质厚度和自身抗体表现出取决于性别的影响.
科学领域:
- 运动生理学 运动生理学
- 免疫学 免疫学 免疫学
- 心血管健康的心血管健康
背景情况:
- 众所周知,耐力训练会影响心血管和免疫功能.
- 对改性脂蛋白对血管健康和免疫内分泌反应的具体影响需要进一步阐明.
研究的目的:
- 研究高耐力训练对血管健康参数的影响.
- 检查训练有素与未训练有素个体对改性低密度脂蛋白 (LDL) 颗粒的免疫内分泌反应.
主要方法:
- 观察性,横截面研究,比较高耐力训练和健康的未经训练的受试者 (n=96).
- 血管超声波评估了大脑动脉内膜介质厚度和流量介导扩张.
- 在ELISA中测量了白细胞间蛋白 (IL-8,IL-10) 和自身抗体 (anti-oxLDL,anti-ApoB-D).
- 质谱分析了皮质和17α-基孕.
主要成果:
- 经过高耐力训练的雄性比未经训练的雄性表现出较小的动脉内心介质厚度;女性没有性别差异.
- 在受过训练和未受训练的群体之间或根据性别之间,流量介导扩张没有显著差异.
- 幽默性免疫反应显示了对LDL分子修饰的自身抗体的同型失衡.
- 在17α-hydroxyprogesterone和心动脉内膜-介质厚度之间发现了反向相关性;在IL-10和流媒体扩张之间发现了直接相关性.
结论:
- 慢性高耐力运动调节血管健康和免疫内分泌参数.
- 这些调制取决于性别,影响着动脉内膜厚度和免疫反应.
- 研究结果表明,运动,免疫力和心血管健康之间存在复杂的相互作用.
相关概念视频
01:20Exercise and Cardiovascular Response
843
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
843
01:27Exercise and Muscle Performance
1.5K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.5K