人类测量和DXA衍生的身体成分测量与成人糖尿病前期相关
Anwar Mohammad1, Ali H Ziyab2, Talal Mohammad3
1Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City, Kuwait anwar.mohammad@dasmaninstitute.org.
BMJ open diabetes research & care
|October 4, 2023
概括
腹部肥胖是糖尿病前期的一个关键风险因素. 内脏脂肪组织 (VAT) 质量与糖尿病前期的相关性最强,这表明其在风险评估中的意义.
科学领域:
- 代谢健康 代谢健康
- 肥胖问题研究研究
- 预防糖尿病 预防糖尿病
背景情况:
- 腹部肥胖是糖尿病前期和糖尿病的主要危险因素.
- 各种指数评估与内脏脂肪相关的腹部肥胖.
- 了解不同脂肪度测量的预测能力至关重要.
研究的目的:
- 评估不同脂肪度测量和糖尿病前期之间的关联.
- 为了比较各种人体测量和人体成分指数的预测准确性,用于糖尿病前期.
主要方法:
- 来自科威特福祉研究的1184名成年人 (18-65岁) 的横截面研究.
- 测量包括BMI,腰部和部的比率,和双能X射线吸收度 (DXA) 总体脂肪,机器人脂肪,骨头脂肪和内脏脂肪组织 (VAT) 质量.
- 糖尿病前期定义为5.7≤HbA1c%≤6.4;计算了调整后的患病率和AUC.
主要成果:
- 增加的BMI,腰部至部比率,总体脂肪,安卓脂肪,骨头脂肪,骨头脂肪和骨头脂肪比率以及VAT质量与糖尿病前期患病率的增加有关.
- 增值税质量显示为0.680的曲线下面积 (AUC) 是预测糖尿病前期的最高值.
- 膝关节脂肪与男性糖尿病前期有关,但与女性无关.
结论:
- 糖尿病前期的患病率随着肥胖度的增加而上升.
- 在评估的指数中,内脏脂肪组织 (VAT) 质量是糖尿病前期最重要的预测指标.
- 脂肪测量,特别是增值税测量,对于识别患糖尿病前期风险的人来说非常有价值.
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