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恶性黑色素瘤过度诊断:一个范围审查

Mille Falk Bjørch¹, Emma Grundtvig Gram^2,3, John Brandt Brodersen^2,3,4

¹Centre of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark millefb@live.dk.

BMJ evidence-based medicine

|October 4, 2023

概括

恶性黑色素瘤的过度诊断很常见,研究估计在29%至60%之间. 皮肤查增加了薄型或现场黑色素瘤的检测,引发了人们对黑色素瘤护理过度诊断的担忧.

科学领域:

皮肤病学皮肤病学
在瘤学瘤学.
流行病学流行病学

背景情况:

恶性黑色素瘤的过度诊断越来越令人担忧.
了解黑色素瘤过度诊断的频率和驱动因素对于有效的患者护理和资源配置至关重要.

研究的目的:

系统地审查关于恶性黑色素瘤过度诊断的经验证据.
确定黑色素瘤过度诊断的频率及其与干预和诊断技术的关联.

主要方法:

根据PRISMA-ScR指南进行了全面的范围审查.
在2022年4月21日,在五个主要数据库 (MEDLINE,Embase,CINAHL,PsycINFO,Cochrane Library) 进行了搜索.
从35个符合条件的经验研究中提取和分析了数据.

主要成果:

审查发现黑色素瘤发病率每年显著增加 (0.39%6.6%),死亡率几乎没有增加.
皮肤查与黑色素瘤的检测增加有关,特别是在现场或细侵袭性类型.
三项研究估计过度诊断的程度,从29%到60%不等.

结论:

流行病学数据强烈表明,恶性黑色素瘤过度诊断的流行率很高.
与皮肤查相关的薄型和现场黑色素瘤的检测增加,需要进一步调查过度诊断的担忧.

关键词:

皮肤学皮肤学公共卫生公共卫生.

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