在未破裂的内动脉瘤的内血管治疗后,视网膜动脉/动脉封闭的风险
Hae Rang Kim1, Min Jeoung Kim2,3, Sunyeup Kim4
1Department of Ophthalmology, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea (the Republic of).
Stroke and vascular neurology
|October 4, 2023
概括
对未破裂的内动脉瘤 (UIA) 进行内血管治疗 (EVT) 可能会增加视网膜动脉/动脉封闭 (RAO) 的风险. 气球微导管和慢性病是相关的危险因素,特别是对类动脉瘤.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 血管外科 血管外科
背景情况:
- 未破裂的内动脉瘤 (UIA) 构成脑血管事件的风险.
- 视网膜动脉/动脉管封闭 (RAO) 是一种严重的并发症,影响视力.
- 治疗UIA和RAO之间的关联需要进一步调查.
研究的目的:
- 评估未破裂内动脉瘤 (UIA) 治疗与视网膜动脉/动脉封闭 (RAO) 的发生率之间的关联.
- 在接受UIA治疗的患者中确定RAO的危险因素.
主要方法:
- 对253,240名UIA患者的全国队列的分析,按治疗分类:观察,微手术剪切或内血管治疗 (EVT).
- 评估RAO发生率和治疗后时间.
- 对RAO的危险比率 (HRs) 和风险因素的评估.
- 详细分析了2569名UIA患者的医院队列.
主要成果:
- 与观察和剪切相比,EVT与RAO的发病率明显高,特别是早期RAO (60天内,HR=4.00).
- 慢性脏疾病和在EVT期间使用气球微导管被确定为RAO的显著风险因素.
- 在医院队列中,RAO发生在0.8%的EVT病例中,但在剪切后没有发生RAO;大多数RAO病例涉及用EVT治疗的副状动脉瘤.
结论:
- 对UIA的内血管治疗可能会增加后续RAO的风险.
- 建议在使用气球微导管用于通过EVT治疗状动脉瘤时谨慎使用.
- 进一步研究优化UIA治疗策略以尽量减少RAO风险是有必要的.
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