吸烟和饮酒与开放角玻璃眼发展的关联:一项回顾性队列研究
Golnoush Mahmoudinezhad1, Takashi Nishida1, Robert N Weinreb1
1Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, California, USA.
BMJ open
|October 4, 2023
概括
酒精消费增加了玻璃眼风险,特别是在男性和非洲血统的人群中. 吸烟也会增加青光眼的风险,特别是在61岁以上的老年人中.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
背景情况:
- 玻璃眼是全球不可逆转的失明的主要原因.
- 饮酒和吸烟等生活方式因素是发展青光眼的潜在可改变的风险因素.
研究的目的:
- 调查酒精消费和吸烟之间的关联,以及眼睛高血压或眼睛中可疑的玻璃眼的周边玻璃眼的发病率.
- 确定可能面临更高风险的特定人口群体.
主要方法:
- 追溯队列研究,包括610名患有青光眼的患者的825只眼睛,在基线时怀疑眼睛和正常视野 (VF).
- 随访时间平均为9年,大眼被定义为连续三次异常VF测试.
- 用单变量和多变量考克斯回归模型来分析生活方式因素.
主要成果:
- 酒精消费与患青光眼的风险增加了57% (HR 1.57).
- 这种风险在男性 (HR 1.92) 和非洲裔个人 (HR 1.79) 中显著更高.
- 吸烟与眼风险增加73% (HR1.73),特别是在老年患者 (年龄>61岁) 中.
结论:
- 酒精消费是青光眼发展的重要风险因素,在男性和非洲裔个人中观察到风险增加.
- 吸烟也增加了玻璃眼风险,年龄是关键的改变因素,对老年人构成更大的威胁.
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