在患有囊性纤维化症的成年人中,使用呼吸阻力修改强制终止的技术
Kathryn Watson1,2, Emma Koenig1, Ashleigh Bannister1
1Physiotherapy Department, Sir Charles Gairdner Hospital, Perth, Australia.
The clinical respiratory journal
|October 4, 2023
概括
将呼吸阻力装置 (ERD) 添加到强制呼吸技术 (FET) 中没有改善囊性纤维化 (CF) 患者的粘液排泄. 然而,一些患者在没有ERD的情况下经历了更好的吐缓解 (EOE).
科学领域:
- 呼吸系统医学 呼吸系统医学
- 肺部病理学 肺部病理学
- 囊性纤维化研究 囊性纤维化研究
背景情况:
- 气道清除技术 (ACT) 对于治疗囊性纤维化 (CF) 和预防不可逆转的气道阻塞至关重要.
- 积极的呼吸压力 (PEP) 和呼吸阻力装置 (ERD) 通过改善附带通风和粘液剪切,有助于粘液清除.
- 这项研究调查了将ERD纳入CF患者的强迫到期技术 (FET) 的有效性.
研究的目的:
- 为了确定在FET期间使用ERD是否会提高CF患者的吐易度 (EOE),吐量和咳频率.
- 为了比较FET的有效性和没有ERD在空气通道清理的个人与CF.
主要方法:
- 经历呼吸道恶化的CF患者参与了这项研究.
- 每位患者完成了两次标准ACT,其中FET组件与ERD或单独执行.
- 收集的数据包括EOE,唾液湿重量和咳频率.
主要成果:
- 在带有ERD和没有ERD的FET之间,没有观察到EOE,唾液湿重或咳频率的显著差异.
- 通常使用PEP设备的参与者的一个子集在不使用ERD时报告了改善的EOE.
结论:
- 在这个小队列中,将FET与PEP口罩相结合并没有显著改善EOE或其他测量结果.
- 建议对更大的患者群体进行进一步的研究,以验证这些发现,并探索ERD辅助FET在CF气道清除中的有效性.
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