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植物介导的银纳米粒子 (Ag-NP) 的优化和生物制造,用于抗菌潜力

Ansar Mehmood¹, Sobia Zahir¹, Muhammad Abdul Rauf Khan²

¹Department of Botany, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, Pakistan.

Journal of biomolecular structure & dynamics

|October 4, 2023

概括

使用Crataegus monogyna叶提取物的银纳米颗粒 (Ag-NPs) 的绿色合成被优化为增强抗菌活性. 更小的Ag-NP (7nm) 对常见的细菌病原体表现出更高的疗效.

科学领域:

绿色化学绿色化学
纳米技术纳米技术
材料科学材料科学材料科学

背景情况:

银纳米粒子 (Ag-NPs) 具有显著的抗微生物特性.
生物制造为传统的化学合成方法提供了一个可持续的替代方案.
Crataegus monogyna 叶子提取物含有适合纳米粒子合成的植物化学物质.

研究的目的:

为了优化Ag-NPs的绿色制造,使用Crataegus monogyna树叶提取物.
研究反应条件对Ag-NP特性的影响.
评估合成的Ag-NPs对病原性细菌的抗菌疗效.

主要方法:

使用AgNO3和Crataegus monogyna树叶提取物合成了Ag-NP.
反应参数 (提取物体积,AgNO3度,pH,温度) 使用一次性一个因素方法进行了优化.
描述涉及紫外线可见光谱,粒子大小分析,扫描电子显微镜 (SEM) 和X射线衍射 (XRD).
评估了抗菌活性对黄金葡萄球菌,Proteus mirabilis,Klebsiella pneumoniae和Pseudomonas aeruginosa进行了评估.

主要成果:

在最佳条件下,产生了7nm球形,晶体的Ag-NPs.
优化反应参数包括20毫升植物提取物,80毫升AgNO3,pH8和100°C.
合成的Ag-NP显示出对所有测试的病原体具有显著的抗菌活性.
较小的Ag-NP尺寸与增强的抗菌疗效相关.

结论:

Crataegus monogyna 叶子提取物是绿色Ag-NP制造的有效媒介.
优化反应条件允许控制Ag-NP大小和抗菌性质.
这种生物制造方法为开发新型抗菌剂提供了一个有前途的途径.

关键词:

克拉泰格斯 (Crataegus monogyna) 是一个单一的动物.绿色合成是一种绿色合成.它具有抗菌活性,具有抗菌活性.反应参数反应参数

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