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Updated: Jul 15, 2025

Profiling of Permethylated Mucin O-glycans Using Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry
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TIM家族免疫检查点的糖蛋白组景观和结构动力学,这些检查点是由SME粘酶激活的

Joann Chongsaritsinsuk1, Alexandra D Steigmeyer1, Keira E Mahoney1

  • 1Department of Chemistry, Yale University, New Haven, CT, 06511, USA.

Nature communications
|October 4, 2023
PubMed
概括

一种新型的粘酶,SME,有助于研究复杂的O-糖化粘素蛋白,如T细胞免疫球蛋白和含有粘素域 (TIM) 家族. 这一突破使得这些关键免疫调节者的详细结构和功能分析成为可能.

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