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Updated: Jul 15, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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模块化,自动合成来自初级基胺的螺旋环四氨基胺

Qiao Cao1, Joshua D Tibbetts1, Gail L Wrigley2

  • 1Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

Communications chemistry
|October 4, 2023
PubMed
概括

这项研究引入了一种新的自动流合成螺旋环四氨基氨基胺 (THN),对于药物发现至关重要. 该方法从简单的起始材料提供了对四个THN异构体的模块化访问.

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