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Updated: Jun 19, 2026

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
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一个高吞吐量屏幕用于碳水化合物反应元素的药理抑制剂

Shaochen You1, Michael J Bollong2

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.

Scientific data
|October 4, 2023
PubMed
概括

研究人员发现了碳水化合物反应元素结合蛋白 (ChREBP) 的新化学抑制剂,这是新陈代谢的关键调节者. 这些工具有助于理解ChREBP.

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Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...