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Updated: Jul 15, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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肺部的替代拼接影响COVID-19的严重程度和呼吸系统疾病

Tomoko Nakanishi1,2,3,4,5, Julian Willett6,7,8, Yossi Farjoun6,9

  • 1Department of Human Genetics, McGill University, Montréal, QC, Canada. tomoko.nakanishi@mail.mcgill.ca.

Nature communications
|October 4, 2023
PubMed
概括

肺组织中的替代拼接显著影响COVID-19的严重程度和易感性. 特定的基因拼接事件,而不是总基因表达,与疾病结果有关,提供了新的治疗点.

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