相关实验视频

Updated: Jul 15, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

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通过HMGB1/SET/HAT1复合体介导的SASH1抑制驱动肺腺癌的葡萄糖分解和转移

Fan Kou1,2,3,4,5, Lei Wu1,2,3,4,6, Yu Zheng2,3,7

  • 1Department of Immunology, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.

Oncogene
|October 4, 2023
PubMed
概括

高流动性组盒子1 (HMGB1) 通过增强糖解和转移促进肺腺癌 (LUAD) 的进展. 这种蛋白质复合物抑制了基因组乙化,抑制了瘤抑制基因并恶化了患者的结果.

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Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

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相关概念视频

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The Retinoblastoma Gene

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The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
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Abnormal Proliferation02:23

Abnormal Proliferation

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Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
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Metastasis02:30

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Small GTPases - Ras and Rho01:24

Small GTPases - Ras and Rho

Ras and Rho are small monomeric GTPases that act downstream of receptor tyrosine kinase (RTK) and regulate various cellular processes. These GTPases switch between active and inactive states by binding to guanine nucleotides.
Three regulatory proteins control their activity:
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