在斯里兰卡,与COVID-19相关的神经疾病
Thashi Chang1, Ruwani Wijeyekoon2, Ajantha Keshavaraj3
1Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. thashichang@gmail.com.
BMC neurology
|October 4, 2023
概括
在斯里兰卡研究了与COVID-19相关的神经疾病,包括中风和脑病变. 在住院期间补充氧气的使用与这些患者的不良结果相关.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,SARS-CoV-2 (COVID-19) 感染的神经并发症是公认的.
- 报告显示,这些现象在南亚地区的流行率很高.
- 这项研究专门调查了与斯里兰卡COVID-19相关的神经疾病.
研究的目的:
- 记录斯里兰卡COVID-19患者的神经系统疾病的频率和频谱.
- 分析COVID-19发作和神经表现之间的时间关系.
- 为了确定与COVID-19相关的神经疾病患者的不良结果相关的因素.
主要方法:
- 从2021年5月到2022年5月,在斯里兰卡进行了一项监控研究.
- 从神经中心招募了184名患有与COVID-19相关的神经疾病的患者.
- 数据通过结构化的电子形式收集,并使用描述性统计和物流回归分析.
主要成果:
- 缺血性中风 (31%) 是最常见的神经症状,其次是脑病 (13.6%) 和吉兰-巴雷综合征 (9.2%).
- 神经疾病在COVID-19发病后的各种时间框架内出现,从几天到几周.
- 在Omicron变种期间,在儿童中增加了脑炎和脑病变病例. 补充氧气需求与糟糕的结果有关 (OR:12.94,p=0.046).
结论:
- 斯里兰卡的COVID-19相关神经系统疾病的范围和发病率反映了全球的发现,中风和脑病变是最普遍的.
- 在住院期间需要补充氧气的需求成为患者表现不佳的重要预测因素.
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