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三种不同的根管密封剂的生物相容性,实验研究实验研究

Ahmad Alfahlawy¹, Manar A A Selim², Hayam Y Hassan³

¹Endodontic Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.

BMC oral health

|October 4, 2023

概括

这项研究评估了老鼠的根管密封剂Well-Root St,GuttaFlow Bioseal和AH-Plus. 所有海动物都表现出极好的生物相容性,在第30天内炎症最小.

科学领域:

生物材料科学生物材料科学
牙科材料牙科材料
组织病理学组织病理学

背景情况:

根管密封剂对于内牙治疗的成功至关重要.
评估新的和现有的密封器的生物相容性对于患者安全至关重要.
了解组织对密封剂的反应,有助于临床材料的选择.

研究的目的:

为了评估三种根管密封剂的生物相容性:Well-Root St,GuttaFlow Bioseal和AH-Plus.
为了比较大鼠皮下组织中这些密封剂的炎症和细胞反应.
为了确定测试密封器的长期组织整合和生物相容性.

主要方法:

在84只雄性大鼠身上,皮下植入了装有密封剂或空的聚乙烯管.
组织组织病理学和免疫组织化学分析7日,15日和30日.
使用ANOVA对淋巴细胞 (CD3+) 和巨细胞 (CD68+) 透的量化.

主要成果:

所有密封剂都诱导了最初的炎症反应和纤维囊形成,到第30天它就消失了.
在早期,AH-Plus的淋巴细胞和巨细胞透率最高.
在整个研究期间,GuttaFlow Bioseal表现出最小的炎症反应.

结论:

所有测试的根管密封剂 (Well-Root St,GuttaFlow Bioseal,AH-Plus) 在大鼠皮下组织中都显示出出色的生物相容性.
对Well-Root St和AH-Plus的初始炎症反应在30天后减弱.
GuttaFlow Bioseal显示了最小的炎症反应,表明有利的生物相容性.

关键词:

这就是AH + AH + AH.生物相容性生物相容性这就是Gutta-Percha.在GuttaFlow的生物密封中.根管道填充材料的使用方法在Well-Root St. 的路上.

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