在COVID-19期间的呼吸器相关肺炎后的肺:一项回顾性多中心队列研究
S Hraiech1,2, K Ladjal3, C Guervilly3
1Service de Médecine Intensive - Réanimation, AP-HM, Hôpital Nord, Marseille, France. sami.hraiech@ap-hm.fr.
Critical care (London, England)
|October 4, 2023
概括
肺部囊使COVID-19患者的呼吸器相关肺炎 (VAP) 复杂化,多微生物VAP和皮的使用是关键风险因素. 建议对持久性VAP进行早期CT扫描,以检测这种严重的并发症.
科学领域:
- 临界护理医学 临界护理医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 接受机械通风 (MV) 治疗COVID-19的患者面临更高风险的呼吸器相关性肺炎 (VAP).
- 肺部是VAP在这个患者群体中研究不足的并发症.
研究的目的:
- 为了确定COVID-19患者中VAP复杂的肺的发生率,特征,危险因素和预后.
主要方法:
- 在法国三个重症监护病房进行了一项观察性回顾性研究.
- 包括的患者已经确认了SARS-CoV-2,急性呼吸衰竭,并且需要MV超过48小时.
主要成果:
- 在507名患者中,326人 (64%) 患有VAP,23人 (7%) 患有肺部.
- 多微生物VAP和皮的使用独立地与肺的发展有关 (分别为OR2.93和4.86).
- 肺部的患者有显著更长的MV持续时间,ICU停留,和更少的无呼吸器日.
结论:
- 肺部的肺炎是COVID-19患者VAP的一个显著并发症.
- 一个多微生物的第一个VAP插曲和皮的使用是显著的危险因素.
- 建议对COVID-19患者进行胸部CT扫描,以确定潜在的肺.
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