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Updated: Jul 15, 2025

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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
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在临床,环境和殖民性凝结体负的Staphylococcus分离物中抗菌剂和mupirocin耐药性
Enas Mamdouh Hefzy1, Tharwat E E Radwan2, Basma M M Hozayen2
1Medical Microbiology and Immunology Department, Faculty of Medicine, Fayoum University, Fayoum, 63514, Egypt. emh01@fayoum.edu.eg.
Antimicrobial resistance and infection control
|October 4, 2023
概括
凝聚性阴性葡萄球菌 (CoNS) 显示出高抗菌性,特别是对化 (BC) 和化 (CTAB). 在医院环境中,赫西丁二甲酸 (CHDG) 对这些机会性病原体更有效.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 凝聚性阴性葡萄球菌 (CoNS) 是重要的机会性和医院病原体.
- 广泛使用的抗菌剂,包括消毒剂,有助于公共卫生挑战.
- 了解CoNS对杀菌剂的敏感性对于感染控制至关重要.
研究的目的:
- 评估CoNS分离物对常见消毒剂的敏感性.
- 在CoNS.中识别消毒剂和抗生素耐药性基因.
- 为了比较不同消毒剂对 CoNS 的疗效.
主要方法:
- 从各种医院来源收集了250个标本.
- 从环境,医疗保健工作者和临床样本中鉴定出55个CoNS分离物.
- 使用标准方法测试了对甲 (BC),甲 (CTAB) 和二甲 (CHDG) 的分离敏感性.
- 通过聚合酶链反应检测出耐药性基因 (qacA/B, smr, qacG, qacH, qacJ, mecA, mupB, mupA).
主要成果:
- 在CoNS临床分离物中观察到高多药耐药性.
- 93%的医疗保健工作者的CONS对BC和CTAB有耐药性,而50%对CHDG敏感.
- 消毒剂耐药性基因 (qacA/B, smr, qacJ) 和抗生素耐药性基因 (mecA) 的患病率显著.
- 鉴定出了S. epidermidis,S. chromogene,S. haemolyticus和S. hominis等种类的冠状病毒.
结论:
- 从医疗保健工作者中分离出来的CoNS呈现出高抗菌剂耐药性基因的流行率.
- 临床 CoNS 感染分离体显示出更大的抗生素耐药性.
- 在这个医院环境中,与BC和CTAB相比,赫西丁二gluconate (CHDG) 显示出更高的疗效.
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