地中海生活方式与2型糖尿病发病率之间的关联:英国生物库前性研究
Javier Maroto-Rodriguez1, Rosario Ortolá1,2, Adrián Carballo-Casla1,2,3
1Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Calle del Arzobispo Morcillo 4, Madrid, 28029, Spain.
Cardiovascular diabetology
|October 4, 2023
概括
采用地中海生活方式,包括饮食和社交习惯,显著降低了英国成年人的2型糖尿病风险. 这种全面的方法,即使在文化上适应,也显示出糖尿病预防的前景.
科学领域:
- 流行病学 流行病学
- 预防医学 预防医学
- 营养科学 营养科学
背景情况:
- 越来越多的证据将地中海饮食与2型糖尿病预防联系起来.
- 关于非饮食地中海生活方式因素和非地中海人口中糖尿病风险的研究有限.
研究的目的:
- 调查综合地中海型生活方式与2型糖尿病发病率之间的关联.
- 通过使用MEDLIFE指数在英国成年人群中评估这种联系.
主要方法:
- 利用了来自112,493名无心血管疾病和糖尿病的成年人 (40-69岁) 的英国生物库数据.
- 使用25项MEDLIFE指数 (食品消费,饮食习惯,体力活动,社交习惯) 评估地中海生活方式.
- 采用Cox比例风险回归,分析糖尿病发病率在中位数9.4年的随访期间.
主要成果:
- 更加坚持地中海生活方式 (MEDLIFE指数) 与2型糖尿病风险降低有关.
- 与最低四分位数 (p-趋势<0.001) 相比,增加MEDLIFE坚持四分位数的危险比率为0.90,0.80和0.70.
- 梅德利夫指数的三个组成部分都独立地与降低糖尿病风险相关.
结论:
- 对地中海型生活方式的更高坚持与英国人口中2型糖尿病发病率降低有关.
- 文化适应的地中海生活方式可能为各种人群的糖尿病预防提供了可行的策略.
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