骨髓介质干细胞衍生的外体对T细胞的免疫抑制作用受损在无塑性贫血中

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Updated: Jul 15, 2025

Assessment of the Immunomodulatory Properties of Human Mesenchymal Stem Cells MSCs
06:20

Assessment of the Immunomodulatory Properties of Human Mesenchymal Stem Cells MSCs

Published on: December 24, 2015

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Shichong Wang1,2, Jiali Huo1, Yilin Liu1

  • 1Diagnostic and Therapeutic Center for Anemic Diseases, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.

Stem cell research & therapy
|October 4, 2023
PubMed
概括

与健康的供体外基因组 (HD-Exos) 相比,来自无塑性贫血患者中介酶干细胞 (AA-Exos) 的外基因组显示免疫抑制受损和治疗效果. 这些AA-Exos表现出改变的miRNA配置文件,这表明它们在无塑性贫血病原和潜在的治疗点中发挥了作用.

关键词:
获得的无塑性贫血.异构体是什么? 异构体是什么? 外构体是什么?免疫调节 免疫调节这是一个微型RNA.

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