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Updated: Aug 7, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
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单细胞测序,空间转录组和牙周炎:重新考虑病变发生和分类

Sleiman Razzouk1,2

  • 1Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, New York, USA.

Oral diseases
|October 5, 2023
PubMed
概括

单细胞RNA测序 (scRNA-seq) 和空间转录组学 (ST) 为牙周炎提供了新的见解. 这些先进的技术有助于理解细胞和基因的变化,以改善诊断和治疗结果.

关键词:
基因组学就是基因组学.牙周疾病 牙周疾病精准医学是一门精准医学.一个单细胞测序测序.空间转录学 空间转录学

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The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...