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影响异常性颗粒性乳头炎复发的因素:系统性审查

Asieh Sadat Fattahi¹, Ghasem Amini¹, Fatemeh Sajedi²

¹Endoscopic and Minimally Invasive Research Center, Department of Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

The breast journal

|October 5, 2023

概括

异常性颗粒性乳腺炎 (IGM) 与怀孕,母乳养和避孕药的使用有关. 抗生素和观察治疗显示,这种罕见的乳腺疾病的复发率较低.

科学领域:

医学科学医学科学医学科学
在瘤学瘤学.
病理学病理学病理学

背景情况:

异常性颗粒性乳腺炎 (IGM) 是一种罕见的良性乳腺疾病,影响生殖年龄的女性.
它的病因仍然未知,有推测与怀孕,母乳养,口服避孕药,高血,吸烟和创伤有关.
不同的治疗方法导致不同的复发率和副作用.

研究的目的:

进行系统性审查和元分析,以了解IGM的原因和复发情况.
确定有效的治疗策略,改善患者的生活质量.

主要方法:

一项系统的文献审查确定了在2022年6月之前对IGM风险因素和复发的合格研究.
从涉及4735名患者的71项研究中提取和元分析了数据.

主要成果:

患者的平均年龄为34.98岁; 79.17%是白人.
常见报告的因素包括怀孕 (92.65%),母乳养 (76.57%),避孕药使用 (22.7%) 和高益生素水平 (19.7%).
整体复发率为17.18%. 这是一个非常可怕的数字. 抗生素 (6.74%) 和观察 (9.4%) 治疗的复发率明显低于其他治疗方法 (p=0.023).

结论:

白人种族,怀孕/母乳养史和避孕激素使用与IGM复发有关.
治疗应该是个性化的,考虑症状严重程度和患者的偏好.
对于复发病例,可以考虑进行手术或免疫抑制疗法.

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