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Updated: Jul 15, 2025

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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在HLA等位基因和与β-乳糖抗生素相关的严重皮肤不良反应之间的关联

Pansakon Wattanachai1, Warayuwadee Amornpinyo2, Parinya Konyoung3

  • 1Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Frontiers in pharmacology
|October 5, 2023
PubMed
概括

这项研究确定了特定的人类白细胞抗原 (HLA) 与β-乳糖抗生素严重皮肤不良反应 (SCARs) 相关的特定基因. HLA-B*50:01显示出最高风险,而HLA-A*02:07可能提供保护.

关键词:
人类白细胞抗原史蒂文斯 - 约翰逊综合征/有毒表皮解剖.急性通用脱血性 pustulosis 的发生.贝塔-乳糖抗生素抗生素是贝塔-乳糖抗生素.药物反应与埃索诺菲利亚和全身症状.严重的皮肤不良反应.

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