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在接受体外受精的妇女体内镜期间的子宫内膜痕:系统性审查和元分析

Evangelos Papanikolaou¹, Nikolaos Peitsidis^1,2, Ioannis Tsakiridis²

¹Assisting Nature IVF Centre and Genetics, Thessaloniki, Greece.

Frontiers in surgery

|October 5, 2023

概括

在体外受精 (IVF) 中胚胎转移 (ET) 之前的宫内膜查 (ES) 显著改善了临床怀孕和活产率. 这种程序可能对接受试管婴儿的患者有益,尽管需要进一步研究特定的患者选择标准.

科学领域:

生殖医学生殖医学
妇科外科手术妇科外科

背景情况:

子宫内膜划伤 (ES) 是在体外受精 (IVF) 中胚胎移植 (ET) 之前进行的一种程序.
它在改善生殖结果方面的有效性,特别是在反复植入失败的情况下,仍在调查中.
对ES的最佳技术和患者选择标准尚未明确定义.

研究的目的:

评估在胚胎移植之前的宫内膜查在宫内膜查期间对生殖结果的有效性.
综合现有研究的证据,以确定催产镜与并发ES对怀孕和活产率的影响.

主要方法:

在多个数据库 (Medline,PMC,ScienceDirect,Scopus,CENTRAL,Google Scholar) 进行了系统的文献搜索,截至2023年4月.
符合条件的涉及透镜和ET前并发ES的研究被纳入了元分析.
分析了12项涉及2,213名患者的研究的数据.

主要成果:

在ET前同时进行子宫内膜查的宫内膜检查导致临床怀孕率 (CPR) 的统计学上显著改善 (RR = 1.50,p < 0.0001).
活产率 (LBR) 也得到了显著的改善 (RR = 1.67,p < 0.0001).
在流产率上没有观察到统计学意义上的差异 (RR = 0.80,p = 0.30).

结论:

带有并发性子宫内膜痕的宫内膜镜可能是一个有益的程序,在ET之前在IVF中提供.
这些发现表明,这种结合方法可能会改善试管婴儿的结果.
建议进一步进行随机试验,以改进患者选择标准并提供更精确的数据.

关键词:

在这个过程中,IVF IVF.在子宫内膜上划伤,痕.通过透镜检查 (hysteroscopy) 来检查身体.重复的植入失败导致了植入失败.生殖结果的结果.

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