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Updated: Jul 14, 2025

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通过设计的膜连接体对T细胞受体的Allosteric抑制

Yujie Ye1, Shumpei Morita2, Justin J Chang3

  • 1Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee at Knoxville, Knoxville, United States.

eLife
|October 5, 2023
PubMed
概括

研究人员开发了一种T细胞受体 (TCR) 的抑制剂,它与其跨膜域结合. 这种抑制剂抑制T细胞信号传递,支持全性TCR激活模型,并为自身免疫性疾病提供潜在的治疗方法.

关键词:
T细胞受体受体的 T 细胞受体.膜生物物理学的生物物理学分子生物物理学分子生物物理学没有,没有,没有.这是一种类.结构生物学结构生物学

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