在成年人视觉皮层的眼睛主导性可塑性的thalamic调节
Yi Qin1,2, Mehran Ahmadlou3, Samuel Suhai1
1Molecular Visual Plasticity Group, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, Netherlands.
eLife
|October 5, 2023
概括
成年人视觉可塑性涉及泰拉马斯,而不仅仅是皮质. 泰拉姆体抑制对于视觉皮层可塑性至关重要,泰拉姆体在成年人视觉学习中发挥着主导作用.
科学领域:
- 神经科学是一个神经科学.
- 视觉系统可塑性 视觉系统的可塑性
- 甲状腺皮层相互作用
背景情况:
- 成年人视觉系统的体验依赖性可塑性主要被认为是一种皮质现象.
- 最近的研究表明,由于感知学习或单眼剥夺等因素,可塑性也发生在 thalamus 的成年背侧生殖核 (dLGN) 中.
- 成年人视觉系统中乳头和皮质可塑性之间的相互作用仍然不太清楚.
研究的目的:
- 为了研究体可塑性对初级视觉皮层 (V1) 的可塑性的影响.
- 确定来自V1的反在调节胸膜可塑性中的作用.
主要方法:
- 在成年小鼠中使用了多电极记录.
- 在DLGN和V1.1中研究的眼球主导性 (OD) 塑性.
- 沉默V1以评估其对乳头皮质可塑性的影响.
主要成果:
- 成年人DLGN可塑性,就像在关键时期一样,需要thalamic突触抑制.
- 缺少甲状腺抑制和可塑性消除了成年人V1.1的OD可塑性.
- 来自V1的反部分驱动在关键时期DLGN的OD转移,但不是在成年期.
结论:
- thalamic突触抑制对于成年人OD可塑性至关重要V1.
- 在V1.中,成年类 thalamus 对体验依赖的可塑性具有显著的,主导性的影响.
- 胸膜可塑性是视觉学习的关键因素,挑战了它仅仅是一个皮质过程的观点.
关键词:
双眼望远镜 双眼望远镜 双眼望远镜有关反的意见反反反.侧面的生殖细胞核这里是鼠标鼠标鼠标鼠标鼠标鼠标.神经科学 神经科学眼睛的主导地位.塑性的可塑性 塑性泰拉姆斯 (thalamus) 是一个神经系统.更多相关视频
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