确定头发中的乙基葡萄化物和大学生自我报告的酒精消费
Jennifer P Pascali1, Arianna Giorgetti1, Guido Pelletti2
1Department of Medical and Surgical Sciences, Unit of Legal Medicine, University of Bologna, via Irnerio 49, Bologna, Italy.
Forensic science, medicine, and pathology
|October 5, 2023
概括
学生的酒精消费受到同龄人的习惯的影响. 一项使用头发乙基葡萄化物 (hEtG) 分析的研究没有发现大学生慢性过度饮酒的证据,这表明需要有针对性的公共卫生举措.
科学领域:
- 法医毒理学 法医毒理学
- 公共卫生 公共卫生
- 生物化学 生物化学
背景情况:
- 年轻成年人的酒精消费受到同龄人的看法的影响,对学术和个人福祉构成风险.
- 大学学生是了解酒精消费模式及其相关风险的关键人口群体.
研究的目的:
- 通过客观的头发乙基葡萄化物 (hEtG) 分析,评估大学生之间的酒精消费.
- 为了调查学生群体中过度饮酒的流行情况.
- 探索酒精消费与人口统计/生活方式因素之间的潜在相关性.
主要方法:
- 三所大学的学生自愿参加.
- 通过问卷和头发乙基糖化物 (hEtG) 的量化评估酒精消费.
- 在固相提取 (SPE) 后使用液态染色学质谱法 (LC-MS/MS) 进行的hEtG分析.
主要成果:
- 77.1%的样本没有可检测的hEtG或≤5ppg/mg的水平,表明不经常或最近没有饮酒.
- 没有学生样本表明慢性过度饮酒 (hEtG ≥30 pg/mg).
- 在hEtG水平与生物性别,学年,BMI或吸烟/咖啡习惯之间没有发现显著的关联.
结论:
- 根据hEtG分析,研究的大学生人口没有广泛的慢性过度饮酒.
- 自我报告的酒精戒断 (2.8%) 明显低于烟草 (65.3%) 或咖啡 (16.7%).
- 学生的高度兴趣表明,以大学为基础的公共卫生促进对酒精消费意识的潜在有效性.
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