10岁时的体力活动水平和大脑形态从10岁到14岁时的变化
Fernando Estévez-López1,2,3, Lorenza Dall'Aglio3,4, María Rodriguez-Ayllon5
1Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
JAMA network open
|October 5, 2023
概括
10至14岁儿童的体力活动增加与杏仁体体积增加有关. 儿童报告的活动也与海马体积增加相关,这表明特定的大脑结构的发展.
科学领域:
- 神经科学是一个神经科学.
- 儿科健康 儿科健康
- 发展生物学 发展生物学
背景情况:
- 身体活动被认为有利于儿童的大脑发育.
- 以前的研究受到了横截面设计和小样本大小的限制.
- 需要纵向数据来理解身体活动与大脑变化之间的关系.
研究的目的:
- 检查身体活动与儿童大脑形态变化之间的纵向关联.
- 研究身体活动如何影响特定的大脑区域,如杏仁体和海马体.
主要方法:
- 在荷兰进行了一项为期四年的基于人口的纵向队列研究 (R世代).
- 包括10岁和14岁的1088名脑部MRI儿童.
- 儿童和照顾者报告的体力活动;通过MRI量化的大脑形态.
主要成果:
- 较高的总体体力活动与桃体体积增加有关 (β=2.6).
- 身体活动与海马体积增加仅在儿童报告时 (β=3.1) 相关.
- 与全球大脑测量结果没有发现任何显著的关联.
结论:
- 童年后期的体力活动与杏仁体的体积增加有关,当儿童报告时,海马体.
- 这些关联表明,身体活动会影响特定的皮质下大脑发育,而不是整体的大脑生长.
- 这些发现支持公共卫生干预措施,促进促进神经发育的体力活动.
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