磁力共振成像指导的骨盆放射治疗:放射科医生的一本入门书
Jim Zhong1, Marta Kobus1, Priyamvada Maitre1
1From the Leeds Institute of Medical Research (J.Z., A.S., A.H.) and Department of Biomedical Imaging (D.B.), University of Leeds, 6 Clarendon Way, Woodhouse, Leeds LS2 9LH, England; Leeds Cancer Centre, St James's University Hospital, Leeds, England (J.Z., A.S., A.H.); Department of Radiation Oncology, Charité Universitätsmedizin Berlin, Berlin, Germany (M.K.); Radiation Therapy Research Group (M.K., P.M., A.D., C.E., M.D., P.H., A.C.) and Division of Cancer Sciences (D.M.), University of Manchester, Manchester, England; and The Christie NHS Foundation Trust, Manchester, England (P.M., C.E., M.D., D.M., P.H., A.C.).
磁共振成像导向辐射疗法 (MRIgRT) 为盆腔瘤提供了卓越的软组织对比. 这种先进的技术可以实现实时适应,有可能改善癌症治疗结果并减少副作用.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医学物理 医学物理
背景情况:
- 放射治疗 (RT) 是癌症治疗的基石,一半的癌症患者接受了它.
- 磁共振成像 (MRI) 整合到RT工作流程中,引入了MRI引导RT (MRIgRT).
研究的目的:
- 让放射科医生熟悉MRI在规划盆腔RT中的应用.
- 讨论各种RT技术以及MRIgRT对治疗范式的影响.
- 审查前列腺癌,宫癌和膀癌中MRIgRT的临床经验和证据.
主要方法:
- 讨论MRIgRT的当前临床经验和证据.
- 治疗病例的插图.
- 突出了诸如实时适应和节省器官风险等好处.
主要成果:
- 与CT相比,MRIgRT为盆腔瘤提供了优越的软组织对比度和运动可视化.
- 实时适应性RT是可以实现的,允许精确准和节省处于风险的器官.
- MRIgRT显示出降低治疗毒性和改善瘤治疗结果的潜力.
结论:
- MRIgRT对移动的骨盆结构特别有益,并提供先进的适应性治疗能力.
- 未来的方向包括使用功能性MRI和放射基因组学的生物驱动的适应性RT.
- 放射科医生必须了解MRIgRT在现代放射瘤学中的作用.
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