在因缺血性中风的机械血栓切除术后,血红蛋白在术期间的降低
Huanwen Chen1,2, Ghasan Ahmad1, Michael S Phipps3
1Division of Interventional Neuroradiology, Department of Radiology, University of Maryland Medical Center, Baltimore, MD, USA.
概括
对中风的机械血栓切除术可能会导致血液流失和贫血. 更多的通过和更长的时间增加了血红蛋白下降,增加了不良结果和死亡的风险.
科学领域:
- 神经学 神经学
- 干预性神经放射学 干预性神经放射学
- 关键护理医学 关键护理医学
背景情况:
- 缺血性中风的机械血栓切除术 (MT) 可以导致手术前的血液流失和血液稀释.
- 血液流失,MT程序因素和临床结果之间的关系尚不清楚.
研究的目的:
- 为了研究在MT和手术特征期间的外流程血红蛋白变化之间的关联.
- 确定新发严重贫血对MT后临床结果的影响.
主要方法:
- 对445名接受MT治疗的患者进行了回顾性分析,以检查前部循环大血管封闭.
- 分析了MT前后的血红蛋白水平;新发严重贫血被定义为MT后的血红蛋白<10 g/dL.
- 在90天后使用修改的兰金尺度 (mRS) 来评估临床结果.
主要成果:
- 在MT后的平均血红蛋白降低为1.27g/dL.
- 增加的血栓切除术通过率和更长的手术时间与更大的血红蛋白下降相关 (p < 0.001和p = 0.002).
- 新发性严重贫血发生在11.5%的患者中,与较高的90天不良结果 (mRS 3-6) 和死亡率 (分别为2.70和2.73) 相关.
结论:
- 术前血红蛋白降低与MT手术强度有关.
- 患有MT后严重贫血的患者面临着明显增加的临床结果和死亡率的风险.
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