亚洲人和白人肺癌患者的查,诊断和初步护理
Xiao Hu1, John W Melson1, Stacey S Pan1
1Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, MA, USA.
The oncologist
|October 5, 2023
概括
亚洲肺癌患者面临较晚的诊断和治疗延迟,但与白人患者相比,他们的生存率相似. 需要进一步的研究,以解决亚洲人群肺癌护理方面的差异.
科学领域:
- 在瘤学瘤学.
- 健康差异 在健康上的差异
- 癌症流行病学 癌症流行病学
背景情况:
- 肺癌是美国亚洲人群癌症死亡的主要原因.
- 关于美国肺癌亚裔患者的特殊护理和治疗结果的数据有限.
研究的目的:
- 为了比较被诊断患有肺癌的亚裔和白人患者的人口统计,疾病特征,查和治疗.
- 评估种族对呈现阶段,治疗开始的时间和整体存活率的影响.
主要方法:
- 在塔夫茨医疗中心2014-2019年间诊断的肺癌患者的回顾性审查.
- 亚洲人和白人患者之间的人口统计,低剂量计算机断层扫描 (LDCT) 查,疾病特征和治疗史的比较.
- 使用顺序逻辑回归,日志等级测试和多变量考克斯回归来评估种族差异的统计分析.
主要成果:
- 亚洲患者更有可能是永不吸烟者,携带EGFR变异,并被诊断为晚期肺癌.
- 亚洲患者经历了更长的治疗开始时间,并且不太可能接受针对癌症的治疗.
- 尽管存在这些挑战,中位数整体存活率相似,多变量分析表明亚洲患者的存活率更好.
结论:
- 与白人患者相比,患有肺癌的亚洲患者患有晚期疾病,并面临治疗延迟.
- 这些在诊断和治疗方面的差异并没有转化为受研究的人群的生存结果较差.
- 需要进一步的研究,以了解和解决肺癌护理和亚洲患者的治疗结果中观察到的差异.
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