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Updated: Jul 14, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
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在cis"良性"SOCS1变体中,与增强的干扰素信号传递和自身免疫有关

Yan Du1, Kailey E Brodeur2, Evan Hsu2

  • 1Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Department of Rheumatology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Journal of autoimmunity
|October 5, 2023
PubMed
概括

SOCS1中的基因变异,个体良性,可以损害I型干扰素信号传递,导致像SLE这样的自身免疫性疾病. 这凸显了综合遗传因素如何导致复杂的自身免疫性疾病.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.在 cis 变体中.干扰素 干扰素 干扰素在SOCS1中,SOCS1是SOCS1.

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