严重和不严重喘的并发症负担:全国观测研究 (FINASTHMA)
Hannu Kankaanranta1, Arja Viinanen2, Pinja Ilmarinen3
1Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
The journal of allergy and clinical immunology. In practice
|October 5, 2023
概括
严重喘患者患有更多的肺炎等并发症,使用皮质类固醇增加了风险. 仔细评估类固醇剂量对于管理严重喘及其相关健康问题至关重要.
科学领域:
- 肺部医学 肺部医学
- 临床流行病学临床流行病学
背景情况:
- 喘影响全球超过3.3亿人,导致严重的发病率,死亡率和社会经济负担.
- 与不严重的喘相比,严重的喘与更高的并发症负担有关.
研究的目的:
- 分析严重与不严重喘患者的并发症负担.
- 调查皮质类固醇使用对喘并发症风险的影响.
主要方法:
- 芬兰 (2014-2018) 193,730名成人喘患者的横截面研究.
- 喘严重程度按吸入性皮质类固醇 (ICS),口服皮质类固醇 (OCS) 和住院次进行分类.
- 在不严重,暂时严重和持续严重的喘组之间比较的并发症患病率.
主要成果:
- 严重喘患者的肺炎,白内障,骨质疏松症,肥胖,心力衰竭和心房的发病率更高.
- ICS和OCS使用表明剂量依赖的关联与几种并发病的风险增加.
- 高水平的OCS使用和并发症与增加的医疗保健资源利用相关.
结论:
- 严重的喘与大量的并发症负担有关,特别是肺炎.
- 皮质类固醇治疗,特别是OCS,与剂量依赖的并发症风险增加有关.
- 临床实践应包括对严重喘患者进行仔细的皮质类固醇剂量评估.
关键词:
心脏病是一种心脏病.白内障是什么?白内障是什么?白内障是什么?伴随性疾病 伴随性疾病皮质类固醇是一种皮质类固醇.医疗保健资源使用情况骨质疏松症是一种骨质疏松症.肺炎是一种肺炎.严重的喘 严重的喘2 型糖尿病 2 型糖尿病更多相关视频
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