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Updated: Jul 14, 2025

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
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在小鼠肝脏中,CRY1/2通过抑制E4BP4调节节律性CYP2A5

Luomin Lin1, Yuwei Huang2, Jinyi Wang3

  • 1College of Pharmacy, Jinan University, Guangzhou, China.

Biochemical pharmacology
|October 5, 2023
PubMed
概括

循环时钟蛋白CRY1和CRY2通过抑制E4BP4.4来调节肝酶CYP2A5的表达和活性. 这一发现澄清了药物代谢节律的机制.

关键词:
在CRY1中使用CRY1.在CRY2中使用CRY2.在CYP2A5A5中.时间药物动力学循环节律是循环节律的节奏.

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