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在B型大动脉解剖患者中性别结果的差异 接受TEVAR治疗的患者
Halim Yammine1, Charles S Briggs1, John R Frederick1
1Sanger Heart and Vascular Institute, Atrium Health, Charlotte, NC.
Annals of vascular surgery
|October 5, 2023
概括
患有B型大动脉剖析 (TBAD) 的女性存在更多的并发症和更大的大动脉直径. 尽管有解剖学上的差异,胸内血管大动脉修复 (TEVAR) 后的结果在性别之间是可比的.
科学领域:
- 血管外科 血管外科
- 心血管研究研究心血管研究
- 医疗成像医学成像
背景情况:
- 胸内血管大动脉修复 (TEVAR) 是一种B型大动脉解剖 (TBAD) 的治疗方法.
- 接受TEVAR治疗结核病的性别之间的表现和结果的差异尚未得到充分证实.
研究的目的:
- 评估接受TEVAR治疗TBAD的患者临床表现,解剖特征和结局的基于性别的差异.
主要方法:
- 一项对186名患者 (112名男性,74名女性) 的回顾性审查,这些患者在2012年至2017年期间接受了TEVAR治疗TBAD.
- 呈现人口统计,并发病,解剖学测量 (大动脉直径,真/假光量) 和术后结果 (存活率,再干预率) 的比较.
主要成果:
- 女性年龄较大,BMI较低,并呈现出更多的并发症 (COPD,高脂血症,吸烟) 和疼痛/高血压.
- 与男性相比,女性呈现出更大的上升大动脉直径和比例较大的真光度,但较小的假光度.
- 3年后的存活率相似 (70%的女性与69%的男性,P=0.042),而女性对重新干预的自由度较低 (48%与58%,P=0.13).
结论:
- 患有TBAD的女性呈现出不同的人口统计和并发症概况以及独特的大动脉解剖特征.
- 尽管存在这些差异,TEVAR在性别之间显示了可比的生存率,这表明在治疗TBAD方面具有相似的疗效.
- 这项研究强调TBAD是一种大动脉病理,在内血管修复后的性别可比结果.
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