偶尔便秘的感知,定义和治疗干预措施:罗马工作组的共识文件
Darren M Brenner1, Maura Corsetti2, Douglas Drossman3
1Northwestern University Feinberg School of Medicine, Chicago, Illinois.
概括
偶尔性便秘,与慢性便秘不同的疾病,是由不常见的,令人烦的症状定义的. 第一线治疗包括聚乙烯甘醇和兴奋剂药,而化合物作为第二种选择.
科学领域:
- 胃肠病学 胃肠病学
- 肠-大脑相互作用的障碍
背景情况:
- 功能性便秘是一种常见的肠-大脑相互作用障碍,影响全球12%.
- 偶尔性便秘是一种新归类的实体,其特点是短暂,重复性便秘发作.
- 本文档提供了基于当前研究的偶尔便秘的工作定义和治疗算法.
研究的目的:
- 为偶尔便秘制定一个工作定义.
- 根据目前的证据,开发偶尔便秘的治疗算法.
- 为了解决文献上的差距和便秘管理的国际差异.
主要方法:
- 一个全面的科学文献综述,重点关注偶尔便秘.
- 使用"罗马四号"标准,为定义建立框架.
- 采用了德尔菲方法,在建议上达成100%的作者共识.
主要成果:
- 定义偶尔便秘是烦人的,不常见的症状没有警报信号,促使医疗管理.
- 建议用聚乙烯甘醇和刺激性药作为一线治疗.
- 建议用于耐火病例的含化合物;对于纤维或便软化剂的数据不足.
结论:
- 偶尔性便秘是一种独特的临床实体,需要标准化的定义和治疗.
- 目前的建议为未来研究流行病学和基于症状的结果提供了框架.
- 需要进一步的研究来验证和完善治疗指南.
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