短时间的皮下注射用于息医学中的症状控制
Paul Howard1,2, Sandra Clawson3,4, John Curtin5,2
1Earl Mountbatten Hospice, Newport, Isle of Wight, UK paul.howard1@nhs.net.
BMJ supportive & palliative care
|October 5, 2023
概括
短时间的皮下注射 (SSCI) 提供了一种安全有效的方法来管理息治疗中的耐火症状. 这项研究发现,SSCI是各种药物输送需求的耐受性良好的选择.
科学领域:
- 抚慰性护理医学 抚慰性护理医学
- 药理学 药理学是指药理学的学科.
- 临床治疗学 临床治疗学
背景情况:
- 在息治疗中,耐药症状带来了重大挑战.
- 现有的药物给药途径可能因药物的特性或患者的病情而受到限制.
研究的目的:
- 评估短时间皮下注射 (SSCI) 的疗效和安全性,以控制息护理患者的耐火症状.
- 探索SSCI对各种剂量策略和药物类型的有用性.
主要方法:
- 在18个月内接受SSCI的111名患者的回顾性图表审查.
- 分析临床笔记,药物记录和输液监测.
- 评估治疗目的,疗效和耐受性.
主要成果:
- 在社区和住院医院设置中,SSCI被管理.
- 用于加载剂量,根据需要的刺激药物的剂量和维持剂量.
- 84种单一药物和51种添加剂的SSCI类型被管理;一般耐受良好,有一个吸收不良的情况.
结论:
- 短时间的皮下注射 (SSCI) 是缓解护理中药物管理选项的宝贵补充.
- 特别有用的SSCI是刺激性或体积大的药物,用于皮下玻尿酸注射.
- 对于半衰期较长的药物,SSCI可以加快达到治疗稳定状态度,从而更快地缓解症状.
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