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[糖尿病和阻塞性睡眠呼吸暂停:一个病例对照研究]

Romina Abelleira1, Carlos Zamarrón1, Vanessa Riveiro1

  • 1Servicio de Neumología, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España.

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概括

阻塞性睡眠呼吸暂停 (OSA) 与糖尿病 (DM) 和糖尿病前期 (preDM) 有关. 年龄,夜间低氧化和过度白天嗜睡 (EDS) 预测DM,而BMI和AHI预测OSA患者的糖尿病前期.

关键词:
阻塞性睡眠呼吸暂停 阻塞性睡眠暂停糖尿病是2型糖尿病的第二种类型.阻塞性睡眠呼吸暂停 阻塞性睡眠暂停糖尿病前期:糖尿病前期.2 型糖尿病 2 型糖尿病

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科学领域:

  • 内分泌学 在内分泌学.
  • 睡眠医学 睡眠医学
  • 心血管医学 心血管医学

背景情况:

  • 阻塞性睡眠呼吸暂停 (OSA) 和糖尿病 (DM) 是普遍存在的,并且经常共存.
  • 它们的联合存在增加了心血管并发症的风险.
  • 经常低诊断OSA和DM/糖尿病前期 (preDM) 之间的关联.

研究的目的:

  • 调查OSA和DM/preDM之间的关联.
  • 在OSA患者中确定DM和DM前的独立预测因子.

主要方法:

  • 采用了一种随机的病例控制研究设计.
  • 参与者根据年龄,性别和体重指数 (BMI) 进行了匹配.
  • 收集的数据包括爱普沃思睡眠度量得分,呼吸暂停-呼吸暂停指数 (AHI) 和氧气脱度指数.

主要成果:

  • 与对照组 (10.1%) 相比,OSA患者中DM的患病率明显高 (18.8%).
  • 在OSA组 (41.8%) 和对照组 (10.6%) 中,糖尿病前期的患病率也显著增加.
  • 59.6%的OSA患者报告过度的白天嗜睡 (EDS),而对照组为24.5%.

结论:

  • OSA与DM和DM前两种疾病都有显著的关联.
  • 在OSA患者中,DM的独立预测因素包括年龄,夜间低氧症和EDS.
  • BMI和AHI被确定为患有OSA的个体中糖尿病前期的预测因素.