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Updated: Jul 14, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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USP46双双酶复合体通过稳定Arrow/LRP6来增加Wingless/Wnt的信号强度

Zachary T Spencer1, Victoria H Ng2, Hassina Benchabane1

  • 1Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.

Nature communications
|October 5, 2023
PubMed
概括

一个双双酸酶复合体稳定了Wnt受体Arrow/LRP6,控制了信号强度. 这种机制对于 Wingless/Wnt 途径在发育和预防癌症中的调节至关重要.

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