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与行为相关的健康风险因素,精神障碍和20年后的死亡率在劳动年龄的普通人口样本中
Ulrich John1,2, Hans-Jürgen Rumpf3, Monika Hanke4
1Institute of Community Medicine, Department of Social Medicine and Prevention, University Medicine Greifswald, W.-Rathenau-Str. 48, 17475, Greifswald, Germany. Ulrich.John@med.uni-greifswald.de.
与行为相关的健康风险因素 (BRFs),如吸烟和不活动,显著预测死亡率. 累积的BRF得分准确地预测了20年来所有原因,癌症和心血管疾病的死亡,而不依赖于心理健康状况.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 死亡风险与累积的行为相关健康风险因素 (BRF) 有关.
- 了解BRF组合对长期死亡率的影响对于公共卫生干预至关重要.
- 心理障碍对这种关系的影响需要进一步调查.
研究的目的:
- 分析BRF和死亡率的程度和组合之间的关系.
- 评估BRF总分对20年来所有原因,癌症和心血管死亡率的预测能力.
- 为了调整心理障碍对死亡率预测的潜在混影响.
主要方法:
- 在德国北部的一个随机人口样本 (18-64岁) 中,评估了BRF和精神障碍 (1996-1997).
- 根据八个BRF等级创建了一个总分.
- 死亡率数据 (所有原因,癌症,心血管) 用官方记录收集了20年 (2017-2018) 的数据.
主要成果:
- BRF总分得分显著预测了所有原因,癌症和心血管死亡率.
- 在调整了年龄,性别和精神障碍后,BRF总分的几率比为1.38 (95% CI 1.31-1.46).
- 特定的BRF组合也显示出对死亡结果的预测价值.
结论:
- 与行为相关的健康风险因素的累积负担是长期死亡率的强有力的预测因素.
- BRFs可以预测死亡率,而不依赖于情绪,焦虑或体形疾病的存在.
- 针对多个BRF的公共卫生战略可以有效降低死亡率.
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