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Updated: Jul 14, 2025

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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针对性地将 furan-2-carboxaldehydes 改造成迈克尔受体类似物,从而产生具有双重抗活动的长效血红蛋白调节剂

Abdelsattar M Omar1,2, Osheiza Abdulmalik3, Khalid M El-Say4

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Chemical biology & drug design
|October 5, 2023
PubMed
概括

新型芳香性化物衍生物被开发用于改善状细胞疾病 (SCD) 治疗的代谢稳定性. 这些化合物共同结合血红蛋白,抑制红细胞形,并破坏形血红蛋白聚合物的稳定性,提供了一个有前途的治疗进展.

关键词:
迈克尔的接受者这是一种抗的抗抗.芳香的阿尔德化物.血红蛋白 血红蛋白 是一个氧气平衡 氧气平衡状细胞疾病是一种状细胞疾病.

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