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抗糖尿病甲福明的抗焦虑作用是由mPFC抑制神经元中的AMPK激活介导的

Yong-Mei Zhang1,2,3, Hai-Chao Zong1,3, Ying-Bei Qi1,2,3

  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Molecular psychiatry
|October 5, 2023
PubMed
概括

甲福明是一种抗糖尿病药物,可以通过在中间前额叶皮层 (mPFC) 中激活AMPK来治疗焦虑. 这种激活恢复GABAergic抑制,减少小鼠的焦虑类行为.

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