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Updated: Jul 14, 2025

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
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通过TCF7L2传递星细胞β-catenin信号,调节突触发育和社会行为

Lukasz Mateusz Szewczyk1,2, Marcin Andrzej Lipiec3,4, Ewa Liszewska5

  • 1Department of Psychiatry and Behavioral Sciences/Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. l.szewczyk@cent.uw.edu.pl.

Molecular psychiatry
|October 5, 2023
PubMed
概括

TCF7L2,一个Wnt/β-catenin通路效应体,对于星球细胞成熟至关重要. 在星球细胞中缺少它会增加突触数量,并增强成年小鼠的社会行为,揭示了神经电路调节中的作用.

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