基于行走视频的统一帕金森病评分表的预测:一项回顾性研究
Katsuki Eguchi1, Ichigaku Takigawa2,3, Shinichi Shirai4
1Department of Neurology, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Hokkaido, Japan. k198762@gmail.com.
BMC neurology
|October 5, 2023
概括
这项研究表明,卷积神经网络 (CNN) 可以从步态视频中预测一些帕金森病 (PD) 症状,但对于严重病例需要更多数据. 远程视频分析为评估PD运动障碍提供了一个有前途的工具.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
- 医疗保健中的人工智能
背景情况:
- 帕金森病 (PD) 诊断和症状评估通常需要亲自临床评估.
- 远程评估PD症状至关重要,尤其是在COVID-19大流行等全球卫生危机期间.
- 基于视频的分析为PD运动障碍的远程评估提供了一个潜在的方法.
研究的目的:
- 评估从步态视频预测统一帕金森病评分表 (UPDRS) 评分的可行性.
- 为此预测任务使用卷积神经网络 (CNN) 模型.
主要方法:
- 追溯分析了74名PD患者的737个步行视频,并获得了相应的UPDRS分数.
- 一个CNN模型被训练来预测UPDRS总部分III分数和特定子分数 (轴心症状,勃拉迪基尼西亚,刚性,震).
- 模型性能使用10%的测试数据集进行评估,通过R2值将预测得分与神经科医生评分的得分进行比较.
主要成果:
- 美国有线电视新闻网 (CNN) 的R2值为0.59的总UPDRS第三部分,0.77的轴性症状,0.56的布拉迪基尼西亚,0.46的刚性,和0.0的震.
- 该模型在预测轴性症状子得分方面表现相对较高.
- 患有严重症状的患者的预测性表现较低,这可能是由于数据有限.
结论:
- 该CNN模型显示了远程PD症状评估的潜力,特别是轴心症状.
- 该模型对总UPDRS部分III分数的准确性中等,对严重PD病例有局限性.
- 为了提高模型的临床适用性和性能,需要更大,更多样化的数据集.
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