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COVID-19相关的急性心肌炎:风险因素,临床结果和早期检测和管理的影响

Shiwani Kamath¹, Mohamad-Hamood T Gomah², Gauthier Stepman¹

¹Internal Medicine, Medical Center of Trinity, Trinity, USA.

|October 6, 2023

概括

急性心肌炎是COVID-19的严重并发症,增加了通风和死亡的风险. 常规的心脏生物标志物测试和对患有潜在心脏病的患者的密切监测对于更好的结果至关重要.

科学领域:

心脏病学心脏病学
传染性疾病传染性疾病
关键护理医学关键护理医学

背景情况:

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 导致COVID-19,这是一种具有多系统并发症的疾病,包括心脏问题.
急性心肌炎是COVID-19的一种已知的并发症,之前的研究表明心脏病患者的死亡率更高.
了解心肌炎和先前存在的心脏病对COVID-19结果的影响至关重要.

研究的目的:

为了确定COVID-19患者是否会患上心肌炎.
评估心肌炎与增加对呼吸系统支持的需求和死亡率之间的关联.
为了评估是否预先存在的心脏病状况会使COVID-19患者的结果恶化.

主要方法:

这是一项多中心的回顾性研究,涉及8162名确诊COVID-19的成年患者.
肌心炎是由TnT和脑性尿素 (BNP) 水平升高所定义的.
统计分析比较了COVID-19患有心肌炎和没有心肌炎的患者之间的住院死亡率和呼吸系统支持率.

主要成果:

在COVID-19患者中,1643名 (20.1%) 患有新发性急性心肌炎.
心肌炎显著增加了需要通风和死亡的风险 (p<0.001).
根本性心力衰竭增加了医院死亡率的1.6倍;非缺血性心肌病增加了死亡率的2.33倍.

结论:

心肌炎是COVID-19的一个显著且可能致命的并发症.
常规的TNT和BNP测试可以帮助识别有风险的COVID-19患者.
预先存在的心脏病与较差的COVID-19结果有关,需要对患者进行警监测.

关键词:

冠状病毒疾病2019 (COVID-19) 是一种新型冠状病毒疾病.在COVID-19中,有很多人.COVID-19和心肌炎是什么意思由于COVID-19引起的心肌炎.肌性心肌炎是一种心肌炎.

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