揭示肝移植患者的药物错误,以提高迫切需要的患者安全
Mohammad S Shawaqfeh1,2, Dalal Alangari1, Ghaliah Aldamegh1
1College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia.
概括
药物错误 (ME) 在肝移植患者中很常见,但大多数都不会造成伤害. 提高患者安全需要识别和解决潜在的药物错误,特别是与移植药物无关的药物错误.
科学领域:
- 医学科学 医学科学 医学科学
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
背景情况:
- 药物错误对患者健康构成重大风险,并增加医疗保健成本.
- 肝移植患者,由于他们的免疫功能受损状态,面临着对ME的并发症的高度脆弱性.
- 这项研究的重点是分析肝移植患者群体中的ME.
研究的目的:
- 审查和分析肝移植患者报告的所有药物错误.
- 为了确定这种脆弱的患者群体中ME的类型,严重程度和促成因素.
- 为改善肝移植患者安全的策略提供信息.
主要方法:
- 检索了2016年1月至2022年8月肝移植患者中报告的所有ME.
- 使用计算机化医生订单输入系统来提取数据.
- 由两名专家药剂师根据类型和严重性风险指数对ME进行分类.
主要成果:
- 总共有407个ME在314个患者记录中被确定,由71名医生提交.
- 大多数ME涉及与肝移植管理无直接关系的药物.
- 抗生素处方显示出最高的错误率 (17.0%),其次是免疫抑制剂 (<14%). C型错误 (无患者伤害) 占所有ME的43.2%.
结论:
- 虽然ME在肝移植患者中很常见,但大多数是C型,与移植特定药物无关.
- 多药和繁重的工作负载可能会导致ME的发生率.
- 实施有针对性的法规和战略对于早期识别和缓解ME至关重要,以提高患者安全.
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